Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10455570 | Brain and Cognition | 2014 | 5 Pages |
Abstract
To elucidate these issues, in this study we analyzed BDNF serum levels in two groups of subjects: patients with trauma exposure who developed PTSD, and subjects with trauma exposure who did not develop PTSD. We found that BDNF serum levels were lower in PTSD patients as compared to related control subjects. Thus, these data suggest that BDNF might be involved in pathophysiology of PTSD and consequently therapeutic approaches aimed at restoring BDNF serum levels may be beneficial to this pathology.
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Authors
Francesco Angelucci, Valerio Ricci, Francesca Gelfo, Giovanni Martinotti, Marcella Brunetti, Gianna Sepede, Maria Signorelli, Eugenio Aguglia, Mauro Pettorruso, Federica Vellante, Massimo Di Giannantonio, Carlo Caltagirone,