Article ID Journal Published Year Pages File Type
10461494 Neuroscience & Biobehavioral Reviews 2013 17 Pages PDF
Abstract
► Cognitive decline occurs in neurodegenerative disorders and during normal aging. ► Resting-state fMRI is a promising neuroimaging tool to address aging and cognition. ► Brain networks are mapped by analyzing resting-state functional connectivity (RSFC). ► Aging most consistently affects the default-mode network, critical for memory. ► Aging impairs RSFC via white matter, dopaminergic and/or β-amyloid dysfunction.
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Life Sciences Neuroscience Behavioral Neuroscience
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