Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10461494 | Neuroscience & Biobehavioral Reviews | 2013 | 17 Pages |
Abstract
⺠Cognitive decline occurs in neurodegenerative disorders and during normal aging. ⺠Resting-state fMRI is a promising neuroimaging tool to address aging and cognition. ⺠Brain networks are mapped by analyzing resting-state functional connectivity (RSFC). ⺠Aging most consistently affects the default-mode network, critical for memory. ⺠Aging impairs RSFC via white matter, dopaminergic and/or β-amyloid dysfunction.
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Authors
Luiz Kobuti Ferreira, Geraldo F. Busatto,