Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10461558 | Neuroscience & Biobehavioral Reviews | 2012 | 12 Pages |
Abstract
⺠BTBR mice show reduced social behaviors, more “alone”, and enhanced autogrooming in a seminatural VBS. ⺠Reductions in nose tip-to-nose tip behaviors (gaze avoidance?) and enhanced crawl under/over in a Social Proximity Test. ⺠Diazepam normalizes social preference and crawl under/over but not nose tip-to-nose tip behaviors of BTBR. ⺠BTBR object preferences and patterned investigations of several objects in order are enhanced. ⺠BTBR shows sharply reduced fractone-associated heparan sulfate, suggesting disturbances of growth and guidance factors.
Keywords
Related Topics
Life Sciences
Neuroscience
Behavioral Neuroscience
Authors
D. Caroline Blanchard, Erwin B. Defensor, Ksenia Z. Meyza, Roger L.H. Pobbe, Brandon L. Pearson, Valerie J. Bolivar, Robert J. Blanchard,