Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10461559 | Neuroscience & Biobehavioral Reviews | 2012 | 13 Pages |
Abstract
- Imaging studies in Alzheimer's disease have focussed on medial temporal lobe changes.
- Metabolic studies show the importance of the parietal lobe.
- We review evidence of involvement of the parietal lobe from various imaging studies.
- The posterior cingulate gyrus is most commonly affected in early Alzheimer's disease.
- A disease model, based on the parietal lobe, highlights the role of myelin breakdown.
Keywords
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Authors
Heidi I.L. Jacobs, Martin P.J. Van Boxtel, Jelle Jolles, Frans R.J. Verhey, Harry B.M. Uylings,