| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10461573 | Neuroscience & Biobehavioral Reviews | 2012 | 16 Pages |
Abstract
⺠GWAS and CNV studies allow better probing of the genetic makeup of major psychoses. ⺠Risk genes include: SZ (ZNF804A; NRGN; TCF4) and BPD (CACNA1C; PBRM1; ANK3; DGKH; NCAN). ⺠Genetic risk loci common to SZ and BPD include ZNF804A, CACNA1C, NRGN, PBRM1. ⺠Large structural deletions and duplications are more likely found in SZ than BPD. ⺠Integrating various platforms to unravel the genetic basis of psychoses is needed.
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Authors
Kok Wei Lee, Puay San Woon, Yik Ying Teo, Kang Sim,