Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10461615 | Neuroscience & Biobehavioral Reviews | 2011 | 23 Pages |
Abstract
â¶ Hypothesis: Depression is triggered by stress-induced brain injury. â¶ The injury repair response has neuroinflammatory and neuroregenerative phases. â¶ Released inflammatory mediators elicit sickness behavior and psychological pain. â¶ Neurotrophin- and neurogenesis- mediated regeneration normally resolves the injury. â¶ However, both neuroinflammation and psychological pain are prone to chronicity.
Keywords
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Authors
Karen Wager-Smith, Athina Markou,