Article ID Journal Published Year Pages File Type
10461678 Neuroscience & Biobehavioral Reviews 2013 15 Pages PDF
Abstract

- Excessive nutrition elicits early hypothalamic, hippocampal and cortical inflammation.
- Hypothalamic-inflammation disrupts energy-balance, insulin secretion and sensitivity.
- Brain insulin resistance and regional (e.g., hippocampal) atrophy evolve.
- Brain dysfunction translates into aberrant control of eating and cognitive decline.
- Brain disease is inseparable from obesity itself.
Related Topics
Life Sciences Neuroscience Behavioral Neuroscience
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