Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10461678 | Neuroscience & Biobehavioral Reviews | 2013 | 15 Pages |
Abstract
- Excessive nutrition elicits early hypothalamic, hippocampal and cortical inflammation.
- Hypothalamic-inflammation disrupts energy-balance, insulin secretion and sensitivity.
- Brain insulin resistance and regional (e.g., hippocampal) atrophy evolve.
- Brain dysfunction translates into aberrant control of eating and cognitive decline.
- Brain disease is inseparable from obesity itself.
Related Topics
Life Sciences
Neuroscience
Behavioral Neuroscience
Authors
Gabi Shefer, Yonit Marcus, Naftali Stern,