| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10461742 | Neuroscience & Biobehavioral Reviews | 2013 | 17 Pages |
Abstract
- MA-ergic neurons send extensive projections to the rest of the brain.
- These neurons exert strong modulatory influence on hippocampal cells.
- MA-ergic systems are characterized by scarce number of cell bodies and long axons.
- These neurons retrogradely transport and are dependent on supply of growth factors.
- This might explain vulnerability of MA-ergic neurons in Alzheimer's disease.
Keywords
5-HTACCVMAPFCDBHNADPAADCAβ5-hydroxytryptamineDATAPP5-HTTNGFMMSESAMP8GPCRDLPFCNBMCOMTVTADOPACDRNPLCOFCMAOaMCITph5HIAANFT5-HTTLPRnucleus basalis magnocellularisIDOMRNMAO-BHDCBPSDhMTMHPG3-methoxy-4-hydroxyphenylglycolTMNL-DOPSl-Amino acid decarboxylase3,4-dihydroxyphenylacetic acid5-Hydroxyindoleacetic acidBDNFMitochondrial DNAG protein coupled receptorl-3,4-dihydroxyphenylalaninel-DOPASNpcamyloid βinsulin-degrading enzymeatomoxetineamnestic mild cognitive impairmentVanillylmandelic acidMini-mental state examIDEindoleamine 2,3-dioxygenaseAlzheimer's diseaseParkinson's diseasesubstantia nigra pars compactatyrosine hydroxylase5-HT transporterDA transporterNeurofibrillary tangleDopamineDopaminergicmtDNASerotoninDown syndromemedial septumdentate gyrusnerve growth factorBrain-derived neurotrophic factorphospholipase Cprefrontal cortexEntorhinal cortexorbitofrontal cortexanterior cingulate cortexdorsolateral prefrontal cortexlocus coeruleusPerforant pathGenome-wide association studiesGWASSelective serotonin reuptake inhibitorSSRIMonoaminemonoamine oxidase Bmonoamine oxidaseMonoaminergicventral tegmental areaNADnorepinephrinenicotinamide adenine dinucleotidenicotinamide adenine dinucleotide phosphatemedian raphe nucleusdorsal raphe nucleustuberomamillary nucleushomovanillic acidtryptophan hydroxylaseHistamineHistidine Decarboxylaseamyloid precursor proteinSingle nucleotide polymorphismSNPHVAcornus ammonisadrenergic receptor
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Authors
Ludwig Trillo, Devsmita Das, Wayne Hsieh, Brian Medina, Sarah Moghadam, Bill Lin, Van Dang, Martha Millan Sanchez, Zurine De Miguel, J. Wesson Ashford, Ahmad Salehi,