Article ID Journal Published Year Pages File Type
10461790 Neuroscience & Biobehavioral Reviews 2013 10 Pages PDF
Abstract
► PFC should be viewed as a source of facilitatory signals that bias competition in brain areas more directly involved in motor execution. ► In TS over-activation of PFC may contribute to the hyper-excitability of motor regions and the occurrence of tics. ► Compensatory changes, leading to enhanced cognitive control in TS, may primarily be implemented by distributed changes in local cortical excitability.
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