| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10465509 | Neuropsychologia | 2011 | 5 Pages |
Abstract
⺠Does APOE É4 exhibit “antagonistic pleiotropy”? ⺠Are É4-related cognitive deficits in old age offset by benefits in young adulthood? ⺠The study, the largest to examine these questions (n = 5445), indicates “No”. ⺠Due to the sample size, unlikely the findings are subject to a Type II error. ⺠Neuropathology may play a key role in É4-cognitive relations in both young and old.
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Authors
David Bunce, Kaarin J. Anstey, Richard Burns, Helen Christensen, Simon Easteal,