| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10465526 | Neuropsychologia | 2011 | 13 Pages |
Abstract
⺠Three major drives converge on the superior colliculus (SC) with disease progression. ⺠Two are inhibition from basal ganglia (BG) and decreased frontal cortex-BG activity. ⺠Finally, SC disinhibition emerge as functional compensation by extra-BG structures. ⺠Parameters reflecting SC disinhibition correlate negatively with some UPDRS subscores. ⺠We propose that saccades can gauge BG function in PD with disease progression.
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Authors
Yasuo Terao, Hideki Fukuda, Akihiro Yugeta, Okihide Hikosaka, Yoshiko Nomura, Masaya Segawa, Ritsuko Hanajima, Shoji Tsuji, Yoshikazu Ugawa,