Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10465643 | Neuropsychologia | 2010 | 10 Pages |
Abstract
Auditory novelty detection can be fractionated into multiple cognitive processes associated with their respective neurophysiological signatures. In the present study we used high-density scalp event-related potentials (ERPs) during an active version of the auditory oddball paradigm to explore the lifetimes of these processes by varying the stimulus onset asynchrony (SOA). We observed that early MMN (90-160Â ms) decreased when the SOA increased, confirming the evanescence of this echoic memory system. Subsequent neural events including late MMN (160-220Â ms) and P3a/P3b components of the P3 complex (240-500Â ms) did not decay with SOA, but showed a systematic delay effect supporting a two-stage model of accumulation of evidence. On the basis of these observations, we propose a distinction within the MMN complex of two distinct events: (1) an early, pre-attentive and fast-decaying MMN associated with generators located within superior temporal gyri (STG) and frontal cortex, and (2) a late MMN more resistant to SOA, corresponding to the activation of a distributed cortical network including fronto-parietal regions.
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Authors
Felipe Pegado, Tristan Bekinschtein, Nicolas Chausson, Stanislas Dehaene, Laurent Cohen, Lionel Naccache,