Article ID Journal Published Year Pages File Type
10466443 Neuropsychologia 2010 10 Pages PDF
Abstract
We hypothesize that faulty executive control is the primary deficit, reflected by the reduced N2 component in the mutation carriers. To compensate for this deficit, mutation carriers change their strategy of speed-accuracy trade-off, in order to dampen the excitability of their lateral motor system. Disease progression might prevent symptomatic PD patients from using this compensatory mechanism, leading to increased disinhibition of their lateral motor system.
Related Topics
Life Sciences Neuroscience Behavioral Neuroscience
Authors
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