| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10480706 | Physica A: Statistical Mechanics and its Applications | 2012 | 14 Pages |
Abstract
⺠Bcl-2 apoptotic switch requires Bax/Bak activation mediated by BH3-only proteins. ⺠The model's ultrasensitivity is negatively related to Bax/Bak spontaneous activation. ⺠The auto-activation of Bax/Bak leads to bistability if mediated by monomeric units.
Keywords
Related Topics
Physical Sciences and Engineering
Mathematics
Mathematical Physics
Authors
TomáÅ¡ Tokár, Jozef UliÄný,