Article ID Journal Published Year Pages File Type
10481646 Physica A: Statistical Mechanics and its Applications 2013 6 Pages PDF
Abstract
Sequence comparison is one of the major tasks in bioinformatics, which can be used to study structural and functional conservation, as well as evolutionary relations among the sequences. In this paper, we introduce the concept of distance frequency of amino acid pairs and propose a new numerical characterization of protein sequences, which converts any protein sequence into a distance frequency matrix. Using this distance frequency matrix, we can compare the similarity of protein sequences. In order to confirm the validity of our method, we test it with two experiments. The results show that our method is effective.
Related Topics
Physical Sciences and Engineering Mathematics Mathematical Physics
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