Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10481646 | Physica A: Statistical Mechanics and its Applications | 2013 | 6 Pages |
Abstract
Sequence comparison is one of the major tasks in bioinformatics, which can be used to study structural and functional conservation, as well as evolutionary relations among the sequences. In this paper, we introduce the concept of distance frequency of amino acid pairs and propose a new numerical characterization of protein sequences, which converts any protein sequence into a distance frequency matrix. Using this distance frequency matrix, we can compare the similarity of protein sequences. In order to confirm the validity of our method, we test it with two experiments. The results show that our method is effective.
Related Topics
Physical Sciences and Engineering
Mathematics
Mathematical Physics
Authors
Zengchao Mu, Jing Wu, Yusen Zhang,