Article ID Journal Published Year Pages File Type
10482013 Physica A: Statistical Mechanics and its Applications 2011 8 Pages PDF
Abstract
► We model the impact of quiescent cells on chemotherapy effectiveness. ► We assume that chemotherapy only affects cell reproduction and induces cell apoptosis. ► Therapy-surviving quiescent cells may become proliferative and restart tumor growth. ► Quiescent cells cause therapy failure even in the absence of acquired resistance.
Related Topics
Physical Sciences and Engineering Mathematics Mathematical Physics
Authors
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