| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10509448 | Drug and Alcohol Dependence | 2013 | 7 Pages |
Abstract
This study suggests that exposure to various opioids carries differential probabilities of altering the highly sensitive neurochemistry of adolescent brains. Methadone exposure disturbs the D2-like receptor's response, indicating a potential risk in administering methadone to adolescents (either for the treatment of opioid dependency/abuse or for pain management). In contrast, buprenorphine appears to have a significantly lower effect on the behavioral sensitivity of D2/D3 dopamine receptors in adolescents.
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Authors
J. William Barwatt, Rebecca S. Hofford, Michael A. Emery, M. L. Shawn Bates, Paul J. Wellman, Shoshana Eitan,