| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10509601 | Drug and Alcohol Dependence | 2013 | 5 Pages |
Abstract
Functional effects of CBRs on MDDCs were shown by CB2 and GPR55 siRNA transfection. Transfected EtOH-treated cells showed significantly higher levels of proinflammatory cytokine production as measured by IL-1β expression. Our results provide insights into alcohol mechanisms of DC regulation and show, for the first time, that alcohol is inducing CNR2 and GPR55 in human DCs.
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Authors
Marisela Agudelo, Adriana Yndart, Marisol Morrison, Gloria Figueroa, Karla Muñoz, Thangavel Samikkannu, Madhavan P. Nair,