Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10510201 | Drug and Alcohol Dependence | 2005 | 22 Pages |
Abstract
The prescription of antidepressants for drug abuse seems only clear for nicotine dependence with or without previous comorbid depression (bupropion and nortryptiline). In alcohol dependence without comorbid depression, the use of any antidepressant seems not justified, while in cocaine dependence has to be clarified. The use of antidepressants in alcohol, cocaine or opioid dependence with comorbid depression needs more studies in well-defined samples, adequate doses and duration of treatment to be really conclusive. Interestingly, SSRIs do not seem to offer significant advantages compared with tricyclic drugs in substance abuse disorders. Differences both related to individual characteristics and specific antidepressant drugs need to be clarified in future studies.
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Authors
Marta Torrens, Francina Fonseca, Gerard Mateu, Magà Farré,