| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10536808 | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics | 2012 | 8 Pages |
Abstract
⺠Construction of IgG1-Fc scaffolds with increased thermal. ⺠Selection from a yeast displayed protein-library after heat incubation. ⺠New protocol allowing stabilization of proteins of already high intrinsic stability.
Keywords
ECDscTCRCD64FcRnADCCCDCSECDSCPBSFACSIgG1antibody dependent cell-mediated cytotoxicitySPRSurface plasmon resonanceDirected evolutionfluorescent activated cell sortingElectronic circular dichroismMHCmajor histocompatibility complexPhosphate-buffered salineAntibody engineeringcomplement dependent cytotoxicityYeast displayResponse unitDifferential scanning calorimetrySize exclusion chromatographyneonatal Fc receptor
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Michael W. Traxlmayr, Maximilian Faissner, Gerhard Stadlmayr, Christoph Hasenhindl, Bernhard Antes, Florian Rüker, Christian Obinger,