Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10536812 | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics | 2012 | 11 Pages |
Abstract
⺠Dual functions of protein have mutually exclusive ferrous and ferric iron states. ⺠Internal binding of an inhibitor competes with external substrate binding. ⺠Radical pathways under control of protein conformation. ⺠Distal histidine flexibility responsible for multiple functions. ⺠Structural confirmation by X-ray crystal structures with inhibitors and Xe.
Related Topics
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Authors
Stefan Franzen, Matthew K. Thompson, Reza A. Ghiladi,