| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10536819 | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics | 2012 | 9 Pages |
Abstract
⺠This study describes the importance of proton transfer from the substrates to oxy-tyrosinase. ⺠During the catalysis, one proton is transferred to base B2 and other to the peroxide group. ⺠The transfer of two protons to the peroxide group probably occurs during suicide inactivation. ⺠The limiting step of the catalysis could be the transfer of the first proton to the peroxide group. ⺠The limiting step for inactivation could be second proton transfer to the peroxide group.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Jose Luis Muñoz-Muñoz, Francisco Garcia-Molina, Jose Berna, Pedro Antonio Garcia-Ruiz, Ramon Varon, Jose Tudela, Jose N. Rodriguez-Lopez, Francisco Garcia-Canovas,