| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10536820 | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics | 2012 | 11 Pages |
Abstract
⺠2,3,4,7,8-PCDF is the most abundant molecule in dioxin-like compounds. ⺠The toxicological biomarkers of 2,3,7,8-TCDD in secreted proteins were evaluated using HepG2 cells. ⺠Protein DJ-1, proteasome activator complex subunit 1 and plasminogen activator inhibitor-3 were validated in rat plasma. ⺠These proteins could be used as potential toxicological biomarkers of 2,3,4,7,8-PCDF.
Keywords
14-3-3 σUDP-glucose 6-dehydrogenasePNPO2-DENucleoside diphosphate kinase A2,3,4,7,8-pentachlorodibenzofuranNMAPAI-1IEFDJ-1PCDFsLMAPolychlorinated dibenzofuransLC-ESI-MS/MSMTTtwo dimensional gel electrophoresistwo-dimensional gel electrophoresissodium dodecyl sulfate-polyacrylamide gel electrophoresisSDS-PAGEBiomarkerisoelectric focusingHepG2 cellProteomicRat plasma
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Sohee Phark, So-Young Park, Seonyoung Choi, Zhi Zheng, Eunkyung Cho, Min Lee, Ji-youn Lim, Jong Bok Seo, Nam Hee Won, Woon-Won Jung, Donggeun Sul,