Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10536860 | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics | 2012 | 9 Pages |
Abstract
⺠Two mutations in the most flexible region of firefly luciferase were designed. ⺠D476N mutation doesn't have any significant effect on thermostability. ⺠D474K mutation destabilized protein. ⺠Flexibility analysis demonstrates that D474K became more flexible than native.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Zahra Amini-Bayat, Saman Hosseinkhani, Rahim Jafari, Khosro Khajeh,