Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10536882 | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics | 2012 | 8 Pages |
Abstract
⺠The original view of lysosomes as exclusively destructive organelles has changed. ⺠Controlled proteolysis in endo-lysosomes is needed for immunity. ⺠Antigen presentation and sensing of some microbial products requires protease action. ⺠Cystatin F may attenuate potentially toxic protease levels in some immune cells.
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Authors
Colin Watts,