Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10536887 | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics | 2012 | 9 Pages |
Abstract
⺠Delivery of granzymes by perforin is not understood. ⺠The two models for delivery do not explain all the experimental data. ⺠This review highlights the major questions that remain in this field.
Keywords
MBVFHL2GranzymePerfringolysin OCCPPFOCI-MPREEA1SNAREGAGHPTSGUVTMHN-ethylmaleimide-sensitive factor attachment protein receptorCDCCTLFITCGranzyme BGRB8-hydroxypyrene-1,3,6-trisulfonic acidhEGAdenovirusearly endosomal antigen 1EndocytosisStreptolysin OsloTemmulti-vesicular bodytransmembrane helicesNatural killer cellendoplasmic reticulumGiant unilamellar vesiclefluorescein isothiocyanateLAMPPLYcytolytic T lymphocytecytotoxic lymphocyteMACTransmission electron microscopyPerforinPropidium iodidePneumolysinPoremembrane attack complexCholesterol-dependent cytolysinGlycosaminoglycancation-independent mannose-6-phosphate receptor
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Sarah E. Stewart, Michael E. D'Angelo, Phillip I. Bird,