| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10536896 | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics | 2012 | 13 Pages |
Abstract
⺠Snake venom metalloproteinases (SVMPs) are highly abundant in many viper venoms. ⺠SVMPs can cause hemorrhage and disruption of hemostasis upon envenomation. ⺠SVMPs and mammalian ADAM/ADAMTS proteins constitute the M12B clan of endopeptidases. ⺠Large SVMPs and ADAMs/ADAMTSs have multiple non-catalytic domains. ⺠These ancillary domains may target the enzyme to specific substrates.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Soichi Takeda, Hiroyuki Takeya, Sadaaki Iwanaga,