Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10536898 | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics | 2012 | 9 Pages |
Abstract
⺠Cellular proteases play key roles in virus entry and vascular hyperpermeability. ⺠Influenza A virus (IAV)-cytokine-protease cycle. ⺠IAV infection results in marked upregulation of cellular trypsins and MMP-9. ⺠Processing of IAV hemagglutinin (HA) is a pre-requisite for viral entry into cells. ⺠Identification of HA processing proteases for highly pathogenic avian IAV.
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Authors
Hiroshi Kido, Yuushi Okumura, Etsuhisa Takahashi, Hai-Yan Pan, Siye Wang, Dengbing Yao, Min Yao, Junji Chida, Mihiro Yano,