| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10536900 | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics | 2012 | 17 Pages |
Abstract
⺠Plasmepsins are aspartic proteases encoded by parasite Plasmodium. ⺠Since these parasites cause malaria, plasmepsins are targets for drug design. ⺠Four plasmepsins are found in food vacuole of Plasmodium falciparum. ⺠Crystal structures of all four enzymes have been solved. ⺠Data on structure and inhibition are summarized here.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Prasenjit Bhaumik, Alla Gustchina, Alexander Wlodawer,