| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10536903 | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics | 2012 | 7 Pages |
Abstract
⺠This review summarises recent work on thrombin structure and function. ⺠Crystallography and NMR studies show that thrombin is a highly flexible enzyme. ⺠This plasticity is important for its function. ⺠Flexibility is related to the zymogen-to-protease conformational change. ⺠Flexibility may be a general concept for regulatory enzymes.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
James A. Huntington,