Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10536987 | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics | 2013 | 8 Pages |
Abstract
⺠HXMS is useful for discovery of intrinisically disordered (ID) regions in proteins. ⺠ID discovery and removal facilitates structure determination. ⺠ID discovery facilitates biopharmaceutical quality control. ⺠HXMS reveals coupled folding and binding of IDPs. ⺠HXMS reveals the regions of IDPs involved in aggregation.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Deepa Balasubramaniam, Elizabeth A. Komives,