| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10537009 | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics | 2013 | 7 Pages |
Abstract
⺠A single stranded DNA binding protein form lactococcal phage p2 is here investigated. ⺠The work is focused on its binding mechanism to DNA. ⺠Molecular Dynamics and Docking showed R15 as the key residue for its binding to DNA. ⺠On this basis an R15A SSBp2 mutant has been produced. ⺠EMSA and AFM confirmed Arg15's crucial role in the binding mechanism of DNA to SSBp2.
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Chemistry
Analytical Chemistry
Authors
Erika Scaltriti, Eugenia Polverini, Stefano Grolli, Elisa Eufemi, Sylvain Moineau, Christian Cambillau, Roberto Ramoni,