| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10537104 | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics | 2013 | 10 Pages |
Abstract
⺠We classify multienzyme complexes based on the presence of scaffolding proteins. ⺠Scaffolding proteins typically allosterically regulate signaling multienzyme complexes. ⺠Scaffolding proteins are rare in metabolic multienzyme complexes. ⺠Allostery plays a key role in the presence and absence of scaffolding proteins. ⺠Scaffolding proteins can control pathway branching in multienzyme complexes.
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Authors
Ruth Nussinov, Buyong Ma, Chung-Jung Tsai,