| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10537105 | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics | 2013 | 6 Pages |
Abstract
⺠Recent works on thermodynamic view of allostery are discussed. ⺠Local closeness is a static, geometry-based predictor of binding sites. ⺠Binding leverage: ligand binding affects conformational changes. ⺠Leverage coupling allows to quantify allosteric communication. ⺠Ideas for design of allosteric drugs are discussed.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Igor N. Berezovsky,