| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10537108 | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics | 2013 | 33 Pages |
Abstract
⺠Knowledge based FoldUnfold predicts the same flexible regions as found by MDFirst. ⺠MDFirst uses atom contact fluctuations from MD to build graphs of protein structure. ⺠Rigid cluster hierarchies are different in thermophiles and mesophiles. ⺠In MD simulations thermophiles are less flexible then their mesophilic homologs. ⺠Salt bridges in protein core contribute to stability and rigidity of thermophiles.
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Authors
Tatyana B. Mamonova, Anna V. Glyakina, Oxana V. Galzitskaya, Maria G. Kurnikova,