| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10537142 | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics | 2013 | 25 Pages |
Abstract
⺠Recent structural and mechanistic studies of DNA glycosylases are reviewed. ⺠DNA glycosylases excise oxidized, alkylated, or deaminated nucleobases. ⺠Five structural folds use base flipping to recognize and remove damage. ⺠A sixth architecture traps destabilized base pairs without a base binding pocket.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Sonja C. Brooks, Suraj Adhikary, Emily H. Rubinson, Brandt F. Eichman,