| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10537159 | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics | 2013 | 13 Pages |
Abstract
⺠Changes in active sites of OASS isozymes modulate pentapeptides recognition. ⺠Pentapeptide affinities depends on P3-P4-P5 for strength and P1-P2 for specificity. ⺠Selective OASS inhibitors, potentially antibiotic agents, might be developed.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Francesca Spyrakis, Paolo Felici, Alexander S. Bayden, Enea Salsi, Riccardo Miggiano, Glen E. Kellogg, Pietro Cozzini, Paul F. Cook, Andrea Mozzarelli, Barbara Campanini,