| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10537162 | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics | 2013 | 8 Pages |
Abstract
⺠Apoprolidase was generated. ⺠Mn(II) was proven to be the cofactor necessary for prolidase activity. ⺠A dinuclear Mn(II)-Mn(II) center was identified in active prolidase. ⺠The Mn(II) ion was demonstrated to be necessary for prolidase structural integrity. ⺠A conformational modification was detected in the transition apo/holoenzyme.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Roberta Besio, Maria Camilla Baratto, Roberta Gioia, Enrico Monzani, Stefania Nicolis, Lucia Cucca, Antonella Profumo, Luigi Casella, Riccardo Basosi, Ruggero Tenni, Antonio Rossi, Antonella Forlino,