Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10537163 | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics | 2013 | 10 Pages |
Abstract
⺠We deal with dengue mechanisms of infection through molecular dynamics. ⺠Specific regions of the Domain III are very flexible, with fingerprint-like features. ⺠These loops compose envelope pores, are coordinated and suggest induced fit behavior. ⺠This point towards sites of relevance in the immunogenicity of dengue. ⺠Successful molecular design to this sites could probably halt infection stages.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
R.O.S. Soares, A. Caliri,