Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10537258 | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics | 2013 | 6 Pages |
Abstract
⺠NGB is an endogenous neuroprotective protein. ⺠NGB overexpression protects neurons against death induced by neurotoxicity. ⺠NGB is hormone-inducible nerve globin. ⺠NGB localization into mitochondria sustains a new neuroprotective mechanism.
Keywords
ERβestrogen responsive elementsNgbVDACAPAf-1MPTPEREHIF-1Aβ17β-estradiolamyloid-β peptidesapoptotic protease-activating factor-1mitochondria permeability transition poreApoptosishypoxia-inducible factor-1Vascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)NeuroprotectionSignal transduction pathwaysNeuroglobinTat proteinvoltage-dependent anion channelEstrogen receptorEstrogen receptor β
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Marco Fiocchetti, Elisabetta De Marinis, Paolo Ascenzi, Maria Marino,