Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10537263 | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics | 2013 | 10 Pages |
Abstract
⺠Zebrafish neuroglobin (Ngb) translocates into ZF4 cells. ⺠Human, but not zebrafish, Ngb protects ZF4 cells against hydrogen peroxide exposure. ⺠Chimeric ZHHH Ngb is a cell-membrane-penetrating protein that rescues ZF4 cell death. ⺠Zebrafish Ngb mRNA is upregulated in amacrine cells 3 days after optic nerve injury. ⺠Zebrafish Ngb protein is increased in both amacrine cells and presynaptic regions.
Keywords
PBSNgbSTXONLINLIPLGCLGAPDHNACDMEMFBSGDIFITCDulbecco's modified Eagle's mediumN-acetylcysteineROSAmacrineG proteindigoxigeninfetal bovine serumsyntaxinRetinaDIGfluorescein isothiocyanateouter nuclear layerinner plexiform layerinner nuclear layerganglion cell layerPhosphate-buffered salineguanine nucleotide dissociation inhibitorMyoglobinNeuroglobinguanine nucleotide-binding proteinglyceraldehyde-3-phosphate dehydrogenaseZebrafishReactive oxygen species
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Yuki Kamioka, Chieko Fujikawa, Kazuhiro Ogai, Kayo Sugitani, Seiji Watanabe, Satoru Kato, Keisuke Wakasugi,