| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10537273 | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics | 2013 | 9 Pages |
Abstract
⺠The Root effect in fish Hbs causes a change in cooperativity and oxygen affinity. ⺠Structures and function of T state Antarctic fish Hb at pH 6.2 and 8.4 are compared. ⺠At low pH ligation causes no structural effects, and cooperativity is abolished. ⺠At high pH, ligation causes a displacement of the switch region CD corner. ⺠A significant degree of cooperativity is associated with tertiary changes.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Luca Ronda, Antonello Merlino, Stefano Bettati, Cinzia Verde, Anna Balsamo, Lelio Mazzarella, Andrea Mozzarelli, Alessandro Vergara,