Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10538527 | Food Chemistry | 2013 | 4 Pages |
Abstract
⺠2-(4-Hydroxyphenyl)propionic acid (2-HPPA) enantiomers were separated by HPLC. ⺠We prepared an optically active 2-HPPA from genistein by strain SY8519. ⺠(S)-2-HPPA was synthesized from (S)-2-phenylpropionic acid. ⺠We determined the stereochemistry of SY8519-producing 2-HPPA as an R-configuration. ⺠Genistein attenuates the leptin-reducing activity by the metabolism to (R)-2-HPPA.
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Authors
Toshio Niwa, Shin-ichiro Yokoyama, Toshihiko Osawa,