Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10538679 | Food Chemistry | 2012 | 10 Pages |
Abstract
⺠The antiangiogenic effects of indole-3-carbinol (I3C) were explored. ⺠Lipopolysaccharide-activated macrophages stimulate tube formation of endothelial cells, and I3C suppresses such enhancement. ⺠These effects are associated with increased production of NO, VEGF, IL-6, and MMP. ⺠Inhibited activations of both macrophages and endothelial cells contribute to the antiangiogenic activity of I3C.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Mei-Lin Wang, Chun-Kuang Shih, Hsiao-Pei Chang, Yue-Hwa Chen,