Article ID Journal Published Year Pages File Type
10538679 Food Chemistry 2012 10 Pages PDF
Abstract
► The antiangiogenic effects of indole-3-carbinol (I3C) were explored. ► Lipopolysaccharide-activated macrophages stimulate tube formation of endothelial cells, and I3C suppresses such enhancement. ► These effects are associated with increased production of NO, VEGF, IL-6, and MMP. ► Inhibited activations of both macrophages and endothelial cells contribute to the antiangiogenic activity of I3C.
Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
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