Low molecular weight flaxseed protein-derived arginine-containing peptides reduced blood pressure of spontaneously hypertensive rats faster than amino acid form of arginine and native flaxseed protein

► Hydrolysis of flaxseed proteins with trypsin and pronase produced arginine-containing peptides. ► Electrodialysis-ultrafiltration led to isolation of an arginine-rich peptide fraction (ARG-PF). ► The ARG-PF exhibited in vitro inhibition of angiotensin converting enzyme and renin activities. ► The ARG-PF had faster hypotensive effects than native protein or amino acid form of arginine.