| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10539327 | Food Chemistry | 2011 | 8 Pages |
Abstract
⺠Matrix metalloproteinase (MMP)-2 degrades extracellular matrix and plays a key role in cancer metastasis. ⺠Reactive oxygen species can enhance and activate MMP activity in cancer cell. ⺠Ethyl acetate fraction (ECE) of a brown alga, Ecklonia cava, is polyphenol-enriched and has high anti-oxidative activities. ⺠ECE strongly inhibits the migration and invasion of lung cancer cell. ⺠ECE suppresses MMP-2 via PI3K/Akt and p38 pathways.
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Authors
Hyunkyoung Lee, Changkeun Kang, Eun-sun Jung, Jong-Shu Kim, Euikyung Kim,