Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10540014 | Food Chemistry | 2011 | 8 Pages |
Abstract
⺠Rutin (50-100 μM) reduced proliferation of GL-15 glioblastoma cells. ⺠Rutin induced a decrease in levels of ERK1/2 phosphorylation in glioblastoma cells. ⺠The majority (87.4%) of glioblastoma cells exposed to 100 μM entered in apoptosis. ⺠Rutin induced astroglial differentiation in remaining glioblastoma cells.
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Authors
B.L. Santos, A.R. Silva, B.P.S. Pitanga, C.S. Sousa, M.S. Grangeiro, B.O. Fragomeni, P.L.C. Coelho, M.N. Oliveira, N.J. Menezes-Filho, M.F.D. Costa, R.S. El-Bachá, E.S. Velozo, G.P. Sampaio, S.M. Freire, M. Tardy, S.L. Costa,