Article ID Journal Published Year Pages File Type
10540354 Food Chemistry 2013 11 Pages PDF
Abstract
► Phillyrin inhibits high glucose-induced lipid accumulation by suppressing fatty acid synthase (FAS). ► Phillyrin inhibits FAS expression through modulation of SREBP-1c activation. ► Phillyrin promotes AMPKα phosphorylation in human HepG2 hepatocytes. ► Phillyrin-induced activation of AMPK is regulated by LKB1.
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Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
Preview
Phillyrin attenuates high glucose-induced lipid accumulation in human HepG2 hepatocytes through the activation of LKB1/AMP-activated protein kinase-dependent signalling
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