Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10540534 | Food Chemistry | 2011 | 8 Pages |
Abstract
⺠We determine the structure features and immunomodulatory activity of the pectic polysaccharide from the stems of the ground thistle Cirsium esculentum Siev. ⺠The backbone of cirsiuman consists of 1,4-D-galactopyranosyluronan blocks interconnected by 1,2-linked l-rhamnose residues. ⺠The side chains attach to the 4-position of the l-rhamnopyranose residues. ⺠We examine the immunomodulatory activity of cirsiuman at oral administration. Cirsiuman abrogates oral tolerance and evokes a predominant Th1 immune response to co-administered protein.
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Authors
Daria S. Khramova, Victoria V. Golovchenko, Alexandre S. Shashkov, Dorjgoo Otgonbayar, Aria Chimidsogzol, Yury S. Ovodov,