| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10540667 | Food Chemistry | 2012 | 8 Pages |
Abstract
⺠Mulberry 1-deoxynojirimycin (DNJ) has therapeutic potency in the suppression of postprandial blood glucose. ⺠Several doses of DNJ are needed to achieve optimal therapeutic effect, due to its short half-life. ⺠A novel method was developed to retard DNJ release using gelatin crosslinked with transglutaminase. ⺠High effective DNJ entrapment, increased AUC and prolonged hypoglycaemic effects were observed in rats.
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Authors
Chaluntorn Vichasilp, Kiyotaka Nakagawa, Phumon Sookwong, Ohki Higuchi, Fumiko Kimura, Teruo Miyazawa,